Asian J. Exp. Sci., Vol. 28, No. 1, 2014; 1-7
Newer Risk Factors for Pre-Mature Coronary Artery Disease in Young Indians
Dr. Rajeev Gupta
Deptt of Cardiology, Gandhi Medical College
Cardiac Science Centre GMC - Bhopal, MP, India - 462001
Abstract : Although a number of conventional risk factors have been identified over the past several decades, the
precise aetiology and mechanisms leading to the development of Coronary Artery Disease (CAD) remain
incompletely understood. Increasing recognition that many patients with established CAD lack these conventional
risk factors has led to a search for additional newer risk factors that may predispose individuals to CAD.
Observational and epidemiological studies have identified a host of new and potential risk factors for athero-
thrombotic vascular disease including increased Carotid Intima Media Thickness, elevated blood levels of
homocysteine, fibrinogen, inflammation and infection, atherogenic lipoprotein phenotype associated with small
low-density lipoprotein. (LDL) cholesterol particles and elevated triglycerides, elevated levels of lipoprotein (a)
(Lpa), insulin resistance syndrome (syndrome X or Reaven's syndrome) and psychosocial factors. Predisposing
genetic polymorphisms are of particular interest.
Key words : Coronary Artery Disease (CAD), Lipoprotein (a) (Lpa), low-density lipoprotein.(LDL), Acute
Coronary Syndrome (ACS)
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Asian J. Exp. Sci., Vol. 28, No. 1, 2014; 9-12
Prediction of Cardiac Risk Factors and Cardiac Events by HbAlc in Diabetes
Mellitus.
Dr. Rajeev Gupta
Deptt of Cardiology, Gandhi Medical College
Cardiac Science Centre GMC - Bhopal, MP, India - 462001
Abstract : The present study has been undertaken to compare the effect of HbAlc level (glycosylated haemoglobin)
on the patients suffering from coronary artery disease (CAD) with and without diabetes. For the present study two
hundred patients were selected who were admitted in hospitals with history of acute cardiac states (unstable angina
diabetes, acute myocardial infarction, heart failure, cardiomyopathy). Patients were divided on the basis of diabetic
mellitus into two groups - Group A (diabetics) and Group B (non diabetics). Patients were followed up for six month.
Out of the 200 patients, 72 were diabetic (group A) whereas 128 were non- diabetic (group B). The mean value of
HbAlc in group A was 8.6 ± 1.7% while in group B was 5.5 ± 0.4%. Risk factors like dyslipidemia, hypertension,
previous history of heart disease and stable CAD like triple vessel disease were found more in group A than in group
B. History of smoking, positive family history of heart disease, and angina as a presenting symptom were more in
group B. Complications like heart failure and post infarction angina occurred significantly higher in patients with
diabetes. In group A, unstable angina, ST elevation myocardial infarction, cardiac failure, accelerated hypertension,
dilated cardiomyopathy and triple vessel disease were significantly higher in proportion of patients with poor
glycemic control (HbA 1c > 7%) compared to patients with HbA1c level < 7%. In group B, 92/128 (71.8%) patients
had HbA1c levels > 5.8%. Severity and complications of heart disease were significantly higher in diabetics and
showed a significant correlation with HbA1c. A large number of non diabetics patients (71.8% ) with acute cardiac
states, had HbA1c values> 5.8%.
Key words :Coronary artery disease, Unstable angina, Acute myocardial infarction, Glycosylated haemoglobin ,
Diabetes mellitus Type II, Hyperglycaemia.
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Asian J. Exp. Sci., Vol. 28, No. 1, 2014; 13-21
Anti-microbial activities of Indian spices with special reference to Bishops weed, Cumin and Star anise.
Minakshi De
Department of Microbiology, Surendranath College,
24/2 Mahatma Gandhi Road, Kolkata 700 009
Email : amitkde@satyam.net.in
Amit Krishna De
Indian Science Congress Association, 14 Biresh Guha Street, Kolkata 700 017
Abstract : Spices have been in use traditionally as insect repellent and antiseptic agents Studies with various
spices and herbs have shown from our laboratory to have inhibitory effect on the growth of various types of
microorganism.
These includes cumin, cinnamon, black cumin, clove, onion, Bishop's weed, chilli, garlic, celery,
basil, tejpat, nutmeg, small cardamom, caraway, turmeric, tamarind, aniseed, black pepper, horse raddish,
pomegranate seeds, cambodge, mustard, rosemary, thyme, oregano and star anise.. Further studies with Cumin,
bishops weed and star anise have shown to contain cuminaldehyde, thymol and anethole respectively as the active
anti-microbial components. This review justices the traditional uses of spices as antiseptic and disinfective agents.
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Asian J. Exp. Sci., Vol. 28, No. 1, 2014; 23-24
Blue Whale Skeletan near Aglachewadi, near Phansad Wildlife Sanctuary,
Raigad District, Maharashtra
Bhatnagar P.S.
Western Regional Centre, Zoological Survey of India, Sector No 26,
Ravet Road, Akurdi, Pune 411 044
Introduction :Blue Whale classified under Order Cetacea and Family
Balenopteridae (Wilson and Reeder,1993) . As per IUCN
redlist (www.iucnredlist.org), it is endangered species,
CITES places it in Appendix I (www.CITES.org), while
Wildlife Protection Act,1972 in India lists it in Schedule II.
Marine mammals found off the Maharashtra coast have
also been listed (Somasekharan and Jayaprakash (1987,
and Bhatnagar, 2012).
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Asian J. Exp. Sci., Vol. 28, No. 1, 2014; 25-30
Current Scenario on Enteric Pathogens from the Coastal Area off Visakhapatnam,
India
K. Ramesh Babu, H. Hima Sailaja, K.V. Siva Reddy, G. Vijaya Pratap,
K.G. Anand and M. Ratna Raju
1
Department of Marine Living Resources, College of Science and Technology
2 Department of Zoology, Andhra University, Andhra University, Visakhapatnam-530 003.
Abstract : The current study aimed to establish information on enteric pathogens from coastal waters of
Visakhapatnam. Eight different species were identified and they are Escherichia coli, Enterococcus species,
Shigella species, Salmonella species, Proteus/Klebsiella species, Vibrio species, Faecal Streptococci, and
Pseudomonas species. The colony count values varied from three different stations for each bacterial species and are
represented in CFU/ml. The colony count values for Faecal coliform ranged from 7 to 39 CFU/ml, 5 to 28CFU/ml
for Enterococcus sps, 10 to 23 CFU/ml for Shigella sps, 5 to 30 CFU/ml for Salmonella sps, 12 to 50 CFU/ml
Proteus/ Klebsiella sps, 13 to 55 CFU/ml for Vibrio sps, 5 to 30 CFU/ml Faecal streptococcus, 3 to 28 CFU/ml for
Pseudomonas sps respectively. Total viable counts varied from 120 to 812 CFU/ml and Total count varied from 15 to
92 CFU/ml. There was a significant difference found in enteric pathogens from three different stations.
Key words: Colony count, Enteric pathogens, Enterococcus, Pseudomonas, Streptococcus.
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Asian J. Exp. Sci., Vol. 28, No. 1, 2014; 31-38
Assessment of fecundity of fish, Macrones vittatus (Bloch, 1794) from Bhategaon
Dam, District Hingoli, Maharashtra State, India
Namrata V. Sunnap, Sanjay Shamrao Nanware * and Dhanraj Balbhim Bhure
Research & Post Graduate Department of Zoology, Yeshwant Mahavidyalaya,
Nanded- 431 602. M.S., India.
Abstract :Present investigation deals with the assessment of fecundity of catfish, Macrones vittatus (Bloch, 1794)
has been collected from Bhategaon Dam, Maharashtra during the period from January 2011 to December 2011. The
minimum number of eggs was 2562 and maximum number was 26316 in 102 mm and 162mm total lengths of fish
respectively. The same number of minimum and maximum fecundity was noticed in of roes in 9265 and 30065 mg
total body weight. The relationship of fecundity with other parameters such as total length (TL), total weight (TW),
ovary weight (OW) and ovary length (OL) were both linear and non linear relationship. The coefficient of
correlation (r) in relation to length (TL), total weight (TW), ovary weight (OW) and ovary length (OL, was 0.92, -
0.11, 0.93 and 0.81 respectively.
Key words: Correlation Coefficient (r), Fecundity, Macrones vittatus,
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Asian J. Exp. Sci., Vol. 28, No. 1, 2014; 39-51
Standard Physical Model and Beyond in Manas
Prof. S.P Gautam
13, Residency Area, Indore, 452001
Email : spgautam1956@gmail.com
Abstract :Since time memorial fundamental particle /god particle/ Bramh-kan has been a matter of anxiety. In
various religious books of different sect this particle is discussed. The recent achievement in Standard Physical
Model at CERN and consequent award of Nobel Prize to the findings further excited the globe for discussion on the
matter. The present article presents the decoded version of god particle in Tulsi-Manas and its similarity with
CERN findings. The interesting part of the article is that the findings of CERN matches to that described in
Manas with a clear lead shown in the field of fundamental particle. Findings of Manas Bramh-kan can guide the
researchers interested in Higgs boson particle to a great extent. Manas guide lines for lead work are mentioned in the
last of the article.
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Asian J. Exp. Sci., Vol. 28, No. 1, 2014; 53-60
Biodiversity of Soil Arthropods of Bhagwan Birsa Zoological Park, Ranchi,
Jharkhand
Anupama Singh, AmitaHembrom & Braj Kishore Sinha
Deptt of Zoology, S S M College, Ranchi University, Ranchi
Email: b_kishoresinha@yahoo.co.in
Abstract :The study aimsto measure the biodiversity, abundance and diversity of soil arthropod community of
zoological parks. The surface soils of five stations of the BhagwanBirsa Zoological Park were collected by set
ecological methods by standardized unit cells of quadrate and corers. Quantity and quality of the soil arthropods
were assessed (Density, abundance, Importance value index (IVI) and Shannon diversity index H). The chemical
and physical characteristics of the soil differed little in all the stations. The density of the texaincreased during rains
and diversity index ranges from2.1 to 2.2. The important taxa were Isoptera, Coleoptera, Hymenoptera, Acari,
Collembolans, especially the Entomobryomorpha and Poduromorpha.
Key words: Biodiversity, soil arthropods, zoological park, quadrates, corer, relative abundance, Shannon diversity
index
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Asian J. Exp. Sci., Vol. 28, No. 1, 2014; 61
Bhopal Gas Tragedy, 1984 .MIC or Hydrogen Cyanide?
M M Gupta
Former Professor of Surgery, Gandhi Medical College, Bhopal
E-3/176, Arera Colony, Bhopal
Introduction : The Bhopal disaster, also referred to as Bhopal Gas
Tragedy, which occurred in the last millennium over 29
years ago, was a catastrophe that has no parallel in the
world's industrial history. Since than, there has been a
controversy whether gas leaked was Methyl isocyanate or
Hydrogen cyanide. The gas leaked at the pesticides plants
of Union Carbide India Limited (UCIL) located in the
thickly populated area hardly 2 km. away from Bhopal
Railway Station.
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