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CONTENTS YEAR 2021 Asian J. Exp. Sci., Vol. 35, No. 2, 2021; 1-8
Nitesh Arora1, Nitin Nahar2, R. K. Jain3, T. N. Dubey4
1Department of Cardiology, Gandhi Medical College, Bhopal-462024, India 2Department of Medicine, Gandhi Medical College, Bhopal-462024, India 3Gastroenterology Unit, Department of Medicine, Gandhi Medical College, Bhopal-462024, India 4Department of Medicine, Gandhi Medical College, Bhopal- 462024, India Abstract :
In the current era, with increasing availability of liver transplant across the country, comes a
lacuna of prioritizing the patients presenting to the hospital for liver transplant. Such prioritization,
although done on a standard basis by MELD (The Model for End-Stage Liver Disease) score in various
countries for optimization of transplant waiting list, such scores show discrepancy in predicting acute in
hospital mortality, as they do not take into account sepsis, inflammatory states and MODS. This is a
comparative study, with aim and objectives to study the descriptive clinico-laboratory markers of
prognosis and their relationship with acute mortality (within 30 days of admission) and in patients of
decompensated cirrhosis and acute-on-chronic liver failure and to determine and compare the diagnostic
performance of these clinicolaboratory markers to ascertain acute mortality (within 30 days of
admission). Methodology: The patients were divided into two groups based on inclusion and exclusion
criteria as subgroup A-Cirrhosis and subgroup B-Acute-on-chronic liver failure, and prognostic
indicators including presentation during admission, SIRS criteria, QSOFA score, serum C-reactive
Protein, neutrophil to lymphocyte ratio, serum sodium levels and MELD score were assessed in terms of
30 day mortality from admission. Conclusion: In patients of cirrhosis presenting features along with
inflammatory markers are better prognostic indicators than the traditionally used MELD score. However,
in patients of ACLF, where inflammatory markers are non specifically increased, the MELD score
appears to be the better prognostic marker for mortality.
Key words : Cirrhosis, acute-on-chronic liver failure, MELD score, Neutrophil to lymphocyte ratio, C- reactive Protein, QSOFA, SIRS, Serum Sodium, Prognostic Markers, mortality.
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Nisha Dhoundiyal1 and Adesh Kumar2
Parasitology Laboratory, Department of Zoology Govt. P. G. College, Kotdwar (Garhwal)-246149, Uttarakhand, INDIA Abstract :
In the present study oviposition behaviour of small pigeon louse, Campanulotes bidentatus
compar were described. The location of eggs on the feathers and in demarcated regions of the host body is
reported. It is suggested that louse prefer abdomen, back and breast feathers for egg laying. Eggs are
generally laid on the lower portion, mostly on after shaft of feathers at an angle of 10-200. A single egg is
counted on a single feather. Egg laying process and egg morphology were also discussed.
Key words : Behaviour, Campanulotes bidentatus compar, egg, feather, morphology, egg laying, oviposition, pigeon louse.
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COVID-19 Cardiac Manifestations and Presentation in Pre-Existing Cardiac Disease
Manu Gupta1*, Anuj Gupta2, Rajeev Gupta3
1Gandhi Medical College, Bhopal- 462024, India
Abstract : The pandemic of COVID-19 is cause of high case fatality in patients with heart disease and hypertension. The thrombotic complication has been noted as a part of acute COVID-19 cardiovascular syndrome. Inflammed coronaries vulnerable to plaque rupture leading to thrombosis or spontaneous coronary artery dissection. The incidence of stress-related cardiomyopathy has been on rising trend during COVID-19 pandemic. In stress-induced cardiomyopathy, the role of acute stress-induced sympathetic over activity leading to catecholamine surge and subsequent myocardial dysfunction in the form of regional wall motion abnormality.
Key words : Acute COVID-19 cardiovascular syndrome (ACovCs), Acute Cardiac Injury (ACI), Regional Wall Motion Abnormality (RWMA).
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Poonam Ahirwar and Manju Tembhre*
Govt. P G College, Seoni, Madhya Pradesh, India.
Abstract : Annona reticulata (custard apple) has been utilized widely in India as traditional medicine for cure of many ailments. Plants of the reticulata species are an important resource of many curative agents like antioxidant, anti bacterial and antimicrobial. Present study reports the wide variety of phytochemicals present in the leaf extract viz. Alkaloids, Terpenoids, Flavonoids, Carbohydrates, Glycosides, Tannins and Phenolic compounds, Amino acids and Proteins. The study also evaluated total phenolic and flavonoid contents for their in vitro antioxidant potential. The DPPH free radical scavenging and hydrogen peroxide assays were employed for assessment of antioxidant property of the leaf extract. The total phenol content of ethanol extract of A. reticulata measured by Folin-Ciocalteau reagent in terms of gallic acid equivalent achieved 11.57±2.057 µg/100 µg Gallic acid. However, the flavonoid content of the plant extract as rutin equivalent achieved 23±3 µg/100 µg. The in vitro antioxidant effect of A. reticulata was estimated by DPPH assay with IC50 value of 0.67 mg/ml.
Key words : Annona reticulata, custard apple, phytochemicals, antioxidant, total phenol, flavonoid.
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Nisha Dhoundiyal* and Adesh Kumar
Parasitology Laboratory, Department of Zoology
Abstract : Small pigeon louse, Campanulotes bidentatus compar were studied in vitro. They were subjected to different temperature i.e. 200C, 250C, 300C, 350C, 400C and 450C and relative humidity i.e. 33%, 50%, 75% and 90% to determine lice longevity, an incubation period of egg, daily egg production and hatching of an egg. The optimum temperature range between 30-400C was found essential for normal survival of C. bidentatus compar. The best suitable temperature and humidity were found to be 75±10C and 75±1%. Temperature above 400C was lethal to adult as well as developing stages of C. bidentatus compar. Egg laying, survival time, incubation and hatching period dropped as temperature and relative humidity increased or decreased mention range (i.e. above 400C and 75% and below 300C and 50%).
Key words : adult longevity, Campanulotes bidentatus compar, incubation period, temperature and relative humidity.
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The Theoretical Study of Electrical Conductivity of Polystyrene Polymer Films under High Pressure
Rajendra Kumar Dixit*, Sandhya Patel
Department of Physics
Abstract : The electrical resistivity and conductivity of polymer materials have been studied experimentally under high pressure by different research groups. In this paper, a formula Log σ = C + α loge (Pc/P) - β (P/Pc) has proposed for the theoretical study of the pressure effects on the electrical conductivity of thin films of polystyrene films. The constant σ is related to intermolecular spacing and β depends on the free path of the electrons. The experimental data have been interpreted with pressure at constant temperature for the polarising field EP = 5, 8, 10 and 12 KV/cm. Under high pressure, it has been found that electrical conductivity shows exponential growth with the increasing polarising field.
Key words : Electro-active polymer, resistivity, High pressure, polystyrene polymer
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Pathological Basis and Clinical Presentations in COVID-19
Nitesh Arora* , B. S. Yadav, Rajeev Gupta, A. Sharma, R. S. Meena, R. K. Singh, A. Jain
1Department of Cardiology, Gandhi Medical College Bhopal- 462001
Abstract : Heart and cardiovascular system is the second most common target organ in patients with COVID-19 after the lungs with 12% acute cardiac injury and 44% arrhythmias and a higher mortality rate in patients with pre-existing heart disease and hypertension. This article reviews the cardiac manifestations and complications in COVID-19 and highlights the major cardiovascular manifestations including myocardial infarction, heart failure, myocarditis, arrythmias, pulmonary thromboembolism which contribute to morbidity & mortality in these patients and may have a long-term impact on their health, which yet needs to be determined.
Key words : COVID 19, heart, Myocardial infarction, Arrythmia, heart failure, cardiac biomarkers, NT ProBNP, Troponin I, VTE (Venous Thromboembolism).
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