AJES
Asian Journal of Experimental Sciences
 
 
AJES


VOLUME 29: ISSUE 1&2

CONTENTS YEAR 2015

Asian J. Exp. Sci., Vol. 29, No. 1&2, 2015; 1-6

 

Rock Lobster Fishery from East Coast of India

 

M. Ratna Raju and D. E. Babu

 

Department of Zoology, College of Science and Technology

Andhra University, Visakhapatnam, Andhra Pradesh, India-530 003

Email: ratlobster@gmail.com

 

Abstract :  The lobster fishery of east coast of India, particularly Andhra Pradesh contributes more than one fourth of total landings of east and west coast of India. The present study was aimed to establish a base line data on the lobster fishery resources of the east coast of India. Periodic field surveys were carried out at 10 different landing centers in east coast (Andhra Pradesh) and the data were collected by direct observation. Common non-mechanized and mechanized crafts were engaged in lobster fishing during the study period (2010-2012). Lobsters are manually caught by gill nets. Six commercially important species of rock lobsters Panulirus longipes, P. homarus, P. penicillatus, P. polyphagus, P. versicolor and P. ornatus are available along the east coast among them P. homarus dominated the landings throughout the study period, with maximum catch in October through November and December followed by P. ornatus. The total rock lobster landings from east coast during the study period were estimated at 26.66 tons

 

Key words : Lobster resources, Monsoon period, Post monsoon period.

 

 

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Asian J. Exp. Sci., Vol. 29, No. 1&2, 2015; 7-10

 

Physico-Chemical Parameters of Coastal Waters of Visakhapatnam, East Coast of India

 

Ramana, V, L. M. Rao and C. Manjulatha

 

Department of Zoology, College of Science and Technology Andhra University,
Visakhapatnam-53003
E-mail : rpta999@gmail.com

 

Abstract : The coastal zone of Visakhapatnam is receiving a sewage waste and industrial effluents owing to intensified industrial and population growth. The physicochemical parameters rainfall, atmospheric temperature, water temperature, pH, salinity and dissolved oxygen seasonal variations were discussed. pH ranges between 7.5 to 8.3. during the course of investigation. It was minimum in July and was highest in October. However, DO was maximum in May (6.7mg/L) while it was minimum in the month of September (4.0 mg/L)

 

Key words : Salinity, pH, Dissolved oxygen, Rainfall.

 

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Asian J. Exp. Sci., Vol. 29, No. 1&2, 2015; 11-14

 

Design and analysis of SU-8 based MEMS Piezoelectric Accelerometer

 

K. Spruthi, P. Divya Bharathi, A. Daisy Rani

 

Department of Instrument Technology , Andhra University, Visakhapatnam,
Andhra Pradesh, India, 530003.
E-mail : kalluri.spruthi@gmail.com

 

Abstract : This paper describes about the design and simulation of piezoelectric accelerometer using Silicon and SU-8 as substrates with Zinc Oxide as piezoelectric material. Here simulation was done using COMSOL Multiphysics. Both mechanical and piezoelectric analysis were done. In mechanical analysis a resonant frequency of 995.2 Hz was attained using silicon as a substrate and a resonant frequency of 589.9 Hz was attained using SU-8 as a substrate. In piezoelectric analysis at a particular eigen frequency of 995.2 Hz a potential of 1.73 mV was obtained using silicon as a substrate and for SU-8 as substrate a potential of 1.31 mV was obtained at an eigen frequency of 589.9 Hz. The piezoelectric accelerometer yields good sensitivity with SU-8 as substrate compared to silicon as a substrate.

 

Key words: Comsol Multiphysics, Piezoelectric Materials, MEMS, Sensitivity, Electric Potential, Resonant Frequency.

 

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Asian J. Exp. Sci., Vol. 29, No. 1&2, 2015; 15-28

 

Impact of Herbal Medicines on Conventional Drugs: An Overview

 

Deeksha Singh , Uttam Singh Baghel , Divya Yadav , Manu Sharma , Rakesh Yadav

 

Khalsa college of Pharmacy, G.T. Road, Amritsar-143002, Punjab
Department of Pharmacy, Banasthali University -304022, Tonk , Rajasthan, India.
E-mail : rakesh_pu@yahoo.in

 

Abstract :People misinterpret natural with safe. Unaware of the fact that herbal medicine contains pharmacological active constituents in unknown quantities people use herbal medicinal products (HMPs) carelessly. In the present scenario, people use conventional medicines with herbal medicines that are used as complementary. Impact of co administration of complementary herbal products with conventional (prescription) drugs can results in severe interactions. Herb drug interaction can occur through either pharmacokinetic or pharmacodynamic mechanisms. Herbs can alter the oral bioavailability of the co administered conventional drug which can result in either synergistic or antagonistic effect on its action. So, the basic need of the present scenario is that physicians and consumers should know about the possible interactions and complications arising due to the concomitant use of conventional and complementary medicines as the use of herbal products have increased significantly. This review covers about the mechanism of herb drug interaction with possible herbs that can interact with the possible drugs and the strategies that can help in the reduction of herb-drug interaction.

 

Key words: Herb-Drug interaction, Herbal medicinal products, Conventional drugs, Cytochrome, Concomitant.

 

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Asian J. Exp. Sci., Vol. 29, No. 1&2, 2015; 29-32

 

Histopathological Changes in the Liver and Kidney of Freshwater Teleost, Channa striatus (Bloch) on Exposure to Lead Nitrate

 

Shivani Sharma , Sadhna Tamot , Vipin Vyas and Pinky Kaur

 

Department of Zoology and Applied Aquaculture, Barkatullah University, Bhopal, India
Department of Zoology, Sadhu Vaswani College, Bairagarh, Bhopal, India
Department of Biosciences, Barkatullah University, Bhopal, India
E-mail id. - shivanifisheries@gmail.com

 

Abstract : The present study was conducted to investigate the histopathological changes in the liver and kidney of freshwater murrel, Channa striatus after exposure to 10mg/l (10% of 96 h LC50) of Lead nitrate for a period of 30 days under laboratory conditions. The resultant histopathological changes in the liver and kidney were recorded by light microscope. The most common changes in the liver of fishes were cyotplasmic vacoulation, cluster formation of hepatocytes and degeneration of epithelial layer. Kidney of fishes exposed to 10 mg/l of Lead nitrate were characterized by deshaped renal tubules, loosening of haemopoietic tissues and degeneration of some tissues. The present investigation illustrates that these histopathological changes would serve useful purpose in evaluating the toxic effects of Lead nitrate.

 

Key words:Heavy metals, Lead nitrate, Histopathology, Channa striatus, Liver, Kidney.

 

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Asian J. Exp. Sci., Vol. 29, No. 1&2, 2015; 33-36

 

Prevalence of Helicobacter pylori Infection in Type 2 Diabetes Mellitus Patients in Central India.

 

Sachin Chittawar , Ram Singh Maniram , Jitendra Sharma , Tribhuvan Nath Dubey

 

Department of Medicine, Gandhi Medical College, Bhopal.

 

Abstract :Helicobacter pylori infection is one of the forerunners in a number of people infected with gastrointestinal disorders. Single point cross-sectional observational study was done to evaluate the association of Helicobacter pylori infection with diabetes. Eighty diabetic patients ( 49 males, 31 females 55.3 12 years) were enrolled in the study . 25(31%) patients were positive for H. pylori and rest 55(69%) patients were negative for the test. There was no gender difference and the awareness of diabetes and its treatment was same in both the groups. Duration of diabetes , glycaemic control and awareness of disease and treatment has got an association of H Pylori infection and type 2 diabetes. Better designed large studies are required to establish the cause and association.

 

Key words: Helicobacter pylori, Diabetes Mellitus,

 

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Asian J. Exp. Sci., Vol. 29, No. 1&2, 2015; 37-41

 

Acetylcholinesterase and its Kinetics in the Diagnosis of Myocardial Infarction

 

Madhavi Gaur, Rajeev Gupta and Santosh Kumar

 

Sant Hirdaram Girls College, Hirdaram Nagar, Bhopal (M.P.)
Associate Professor, Department of Cardiology, Gandhi Medical College, Bhopal (M.P.)
Former Vice Chancellor, Dr. H.S. Gour University, Sagar (M.P.)

 

Abstract :Myocardial Infarction (MI) has been diagnosed on the basis of enzyme assay such as CK-MB, SGOT, LDH 1 and troponin I & troponin T in addition to clinical findings, ECG changes and Echocardiographic changes. In the present study another enzyme AChE has been taken to estimate the damage of myocardium because heart is richly innervated by cholinergic nerves. Along with the study of AChE enzyme kinetics will help to ascertain the salvage of myocardium, which will affect the contractility of myocardium. The CK-MB & SGOT levels were found to be increased in correlation with ST- elevation in ECG tracings. In the present study the Km was increased from 2.76 x 10 -3 M to 4.5 x 10 -3 M. However, the AChE activity was inhibited as the activity is inversely proportion to Km.

 

 

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Asian J. Exp. Sci., Vol. 29, No. 1&2, 2015; 43-50

 

Exploration Of Oculo-Antihypertensive Activity In Panex ginseng Extract : An Experimental Study

 

Mahendra Kumar , Ranjit Singh , Neeraj Masand , Kuldip Kumar Saxena

 

Dept of Pharmacy, LLRM Medical College Campus, Meerut,
School of pharmacy Shobhit University Meerut,
Deptt of pharmacology L.L.R.M. Medical College Meerut.
Email:mahendra1129@yahoo.co.in

 

Abstract :The present study was carried out to evaluate the oculo hypotensive antihypertensive effect of aqueous extract of Panex ginseng (PGE) in experimental model of glaucoma. The study was conducted in rabbits which were divided to constitute 3 experimental models viz. normotensive, water loading induced oculo-hypertensive (acute) model and steroid induced (chronic) model using Timolol 0.25% as standard. In normotensive model, effect of PGE (0.25%, 0.5% and 1.0% w/v) on intra-ocular pressure (IOP) was recorded every hour for 8 hours with the help of tonometer whereas in water loaded and steroid induced model, the effect of PGE (1% w/v) on IOP was evaluated after inducing ocular hypertension with the help of oral administration of water (70 mg/kg) and prednisolone 1% eye drops respectively. The effect of PGE (0.25%, 0.5% and 1.0% w/v) on intra-ocular pressure (IOP) was recorded in water loading model at every 15minfor two hours and in steroid induced model at every hour for 8 hours. The aqueous leaf extract of Panex ginseng showed reduction in normotensive animals when used topically in concentration of 0.25% (w/v), 0.5% (w/v) & 1.0% (w/v) concentration respectively. The maximum effect was observed in the concentration of 1.0% (w/v) PGE. This concentration was further evaluated in water loaded (acute) and steroid induced (chronic) ocular hypertensive model. It was observed that a maximum mean difference of 29.0 mm of Hg was found between vehicle treated eyes and 1% PGE treated eyes in acute model (p < 0.0001) after 75 minutes whereas a maximum mean IOP reduction of 35.4 mm of Hg was observed in chronic model (p < 0.0001) after 3 hours of test drug administration.

 

Key words: Glaucoma, Ocular hypertension, Cannabis sativa, Timolol.

 

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Asian J. Exp. Sci., Vol. 29, No. 1&2, 2015; 51-58

 

Effect on the Lipid Profile of Lifestyle, Diet and Exercise.

 

Rajeev Gupta

 

Associate Professor, Cardiology, Gandhi Medical College & Associated Hamidia Hospital,
Bhopal

 

Abstract : This is a clinical based correlation study to the associations between lifestyle, diet, exercise and the serum lipid profile. The study included retrospective analysis of history and investigation of participants comprising 200 men and women above 30 years of age from a disease-free population and included healthy subjects visiting the clinic at Bhopal MP, India. Among the participants of the study, 25.3% of the males and 44.7% of the females had hypercholesterolaemia. Body weight was significantly associated with higher total cholesterol and low-density lipoprotein (LDL) cholesterol. Of the subjects studied, males had a higher mean calorie and fat intake than the females. A positive association was observed between waist circumference and both total cholesterol and LDL cholesterol. Waist circumference was also positively correlated with systolic and diastolic blood pressure and triglycerides. There was a significant difference in the total cholesterol levels of subjects who exercised and those who were not involved in any physical activity. There was a significant difference between the high-density lipoprotein (HDL) cholesterol values of the subjects based on exercise levels. High-density lipoprotein cholesterol levels were significantly higher in males than in females and this is corroborated by the finding of increased exercise levels in males. Duration of exercise had a significant impact on the total cholesterol levels. Our results confirm that diet and exercise significantly affect the serum lipid profile. Obesity and overweight constitute a risk factor for the development of hypercholestero-laemia and hypertriglyceridaemia.

 

Key words: Low density lipoprotein (LDL), High density Lipoprotein (HDL), Cardiovascular disease (CVD), Coronary Artery Disease (CAD), Obesity

 

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AJES