AJES
Asian Journal of Experimental Sciences
 
 
AJES

 

 

 

CONTENTS YEAR 1985

 

Asian J. Exp. Sci., Vol. 1, No. 1, 1985; 1-33

The Bhopalator: A Molecular Model of the Living Cell

Sungchul Ji

Department of Pharmacology and Toxicology,
College of Pharmacy,

Rutgers University, Piscataway,
New Jersey 08854, U.S.A.

 
Abstract: The cell is the smallest and simplest structural unit exhibiting the property of life. In order to provide a microscopic description of life, a molecular model of the living cell has been formulated. The model consists of three classes of structures that are confined within the space bounded by the cell membrane - nucleic acids for storage and transfer of genetic information, enzymes for storage and transfer of energy and genetic information and the dissipative structures of Prigogine regarded as the ultimate form of the expression of the genetic information. These structures with widely varying-stabilities mutually interact to form a superstructure called the Bhopalator that has the emergent property of being able to interact with its environment to fulfill its biological functions. The entity that mediates the interactions between nucleic acids, enzymes and dissipative structures is postulated to conform on a concept originally proposed by Volkenstein and by Green and Ji in 1972 and extend in this communication to include genetic information. The molecular model of the living cell so constructed enables one to combine molecular genetics, enzymology and the dissipative structures in a coherent manner on the basis of a unified theoretical framework so that biology is brought one step closer to chemistry and physics.

 

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Asian J. Exp. Sci., Vol. 1, No. 1, 1985; 34-45

Relationship between Corpus Allatum, Adipose Tissue and Haemolymph Protein Concentration in Danais chrysippus Linn.

S.C. Pathak1, R.N. Shukla2 and D.P. Agrawal3

1. Department of Biological Sciences,
Rani Durgavati University, Jabalpur (M.P.)

 

2. School of Studies in Environmental Biology,

A.P.S. University, Rewa (M.P.)

 

3. Department of Zoology,

Government Degree College,

Lansdown, Jaiharikhal,

Garwal (U.P.)

 

Abstract: The state of the corpora allata of Donais chrysippus has been studied during the first six days of the adult life. During the same period, adipose tissue of the insect has been observed and haemolymph protein concentrations have been determined with a view to check any possible correlation and the influence of CA on the process of vitelliogenesis. There appears to be no direct involvement of the gland in the process of oocyte growth and maturation.

 

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Asian J. Exp. Sci., Vol. 1, No. 1, 1985; 46-52

Possible Factors Responsible for Lysosomal Release from Normal and Diabetic Polymorphonuclear Leukocytes

Suresh N Chari1, N. Nath2 and A.B. Rathi2

1. Department of Biochemistry,

Government Medical College, Nagpur.

 

2. Department of Biochemistry,

Nagpur University, Nagpur.

 

Abstract: Normal and diabetic postgranular supernatants were separated from PMNL and subjected to various physical and chemical treatments before incubation with large granular fraction. The effect of these pretreatments on the release of lysosomal enzymes was then assessed by measuring the activity of B-glucuronidase. The participation of a factor in both normal and diabetic postgranular supernatant having a proteinous characteristics could be detected since, the release was affected by a non-lipid, nondialysable, thermostable (till 80º for 10 min) and ammonium sulfate precipitable (at 20-30%) component. This common protein factor was found to possess no extra capability of releasing lysosomal enzyme under the diabetic state. Pretreatment of normal and diabetic post granular supernatant with superoxide dismutase or horse radish peroxidase did not affect the release of lysosomal enzymes from normal or diabetic PMNL. However, pretreatment with mannitol retarded the release of lysosomal enzyme, the effect being more pronounced in the diabetic state. It was therefore concluded that OH radicals were involved in the lysosomal fragility of diabetic PMNL.

 

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Asian J. Exp. Sci., Vol. 1, No. 1, 1985; 53-57

Effect of Hydration and Dehydration on the Neurosecretory System of Dysdercus

D.P. Gupta and S.A. Faruqui

Department of Zoology,

Dr. H.S. Gour University,

Sagar-470003 (M.P.)

 

Abstract: The effect of hydration and dehydration on the median neurosecretory cells of the pars intercerebralis region of the brain of Dysdercus has been noted. It is suggested that the diuretic hormone in this insect is a part of the final product, after the NSM has been enriched with the CC secretion.

 

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Asian J. Exp. Sci., Vol. 1, No. 1, 1985; 58-65

Eutrophication and Fish Mortality in Rewalsar Lake, Himachal Pradesh

R. Singh, S.M. Misra and B.K. Agarwal

Department of Biosciences,

Himachal Pradesh University,

Summer Hill, Simla-171005

 

Abstract: An attempt has been made to study the impact of eutrophication on fish population. The causes of heavy fish kill has been summarised on the basis of observations recorded during the course of investigation. The study revealed that luxuriant shoreline rnacrophytic vegetation reduces the intensity of macronutrients which caused depletion in oxygen contents from surface towards bottom. Dissolved oxygen contents in diurnal changes in hypolimnion were found in traces which can be a cause of fish mortality. This condition caused mortality about 20,000 individuals of Punctius ticto and Punctius sarana during early summer (April, 1984). During rainy season (August, 1983) a similar situation had occured in which small and large fishes were killed. The following phytoplankton, Melosira granulata, Scenedesmus, Raphadiosis, Peridinium and Microcystis and Zooplankton Keratella volga, K. cochlaris, Filinia opeliensis, Brachinonus coudatus, Daphnia magna were recorded with dominance of Rotifers which indicated entrophic conditions of the lake.

 

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Asian J. Exp. Sci., Vol. 1, No. 1, 1985; 66-67

Determination of Diffusion Coefficients of Metal Ions

S. Qureshi

Government Science and Commerce College,

Benazir, Bhopal.

 

Abstract: The diffusion coefficient (D) of Cr3+ was determined in 0.5 M H2SO4 and was found to be 5.16  10-6 cm2/s. The value of D for Ti3+ in 1.0 M HCl was determined to be 7.14  10-6 cm2/s.

 

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Asian J. Exp. Sci., Vol. 1, No. 1, 1985; 68-70

Complexation of Zn (II) with Tolbutamide, an Oral Antidiabetic Drug

S.A. Iqbal and Rashida Qureshi

Research Laboratories of Chemistry,

Safia College, Bhopal-462001 (M.P.)

 

Abstract: Tolbutamide (Restinon), an oral antidiabetic agent, forms 2:1 complex with zinc acetate inaloholic medium as indicated by conductometric titrations and further verified by Job's method of continuous variation. Analytical results are in favour of 2:1 ratio between ligand & metal. The structure assigned to the complex is supported by I.R. spectral data.

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